TRIPLE-CLASS REFRACTORY MULTIPLE MYELOMA
What is triple-class refractory
Multiple Myeloma?
If you’ve had to change your treatment for multiple myeloma, it may be because your disease has relapsed or come back.2 It is common for multiple myeloma to develop a resistance over time, so medicines you are taking no longer work.1 This is often referred to as relapsed/refractory multiple myeloma.3 A patient’s multiple myeloma is said to be triple-class refractory (TCR) if it is no longer responding to at least one therapy in three treatment classes:4

Refractory is when a cancer does not respond to current or previous treatments. 7

Triple-Class
Refractory Multiple Myeloma Is Growing
When multiple myeloma patients are refractory to at least one therapy in three treatment classes, they become Triple-Class Refractory (TCR).4 If you are TCR, you are not alone. The number of people who are refractory after two lines of treatment (2L), three lines of treatment (3L), or even four or more lines of treatment (4L+) has been growing steadily over the past several years.
